 | Albert Finney als Dewey Wilson |
 | Diane Venora als Rebecca Neff |
 | Edward James Olmos als Eddie Holt |
 | Gregory Hines als Whittington |
 | Tom Noonan als Ferguson |
 | Dick O'Neill als Warren |
 | Dehl Berti als Old Indian |
 | Peter Michael Goetz als Ross |
 | Sam Gray als Mayor |
| Ralph Bell als Commissioner |
| Max M. Brown als Christopher van der Veer |
| Anne Marie Pohtamo als Pauline van der Veer |
| Sarah Felder als Cicely Rensselaer |
 | Reginald VelJohnson als Morgue Attendant (as Reginald Vel Johnson) |
 | James Tolkan als Baldy |
 | John McCurry als Sayad Alve |
| Chris Manor als Janitor |
 | Donald Symington als Lawyer |
| Jeffery Ware als Interrogation Operator |
| E. Brian Dean als Fouchek |
| Jeffery V. Thompson als Harrison (as Jeffery Thompson) |
 | Victor Arnold als Roundenbush |
 | Frank Adonis als Scola |
| Richard Minchenberg als Policeman |
 | Raymond Serra als Detective (as Ray Serra) |
| Thomas Ryan als Detective |
| Tony Latham als Victim |
| David Connell als Victim |
 | Jery Hewitt als Victim |
 | Roy Brocksmith als Fat Jogger in Park (as Ray Brocksmith) |
 | Michael Wadleigh als Terrorist Informer |
| Joaquin Rainbow als Native American |
| John Ferraro als Native American |
| Rino Thunder als Native American |
| Glenn Benoit als Native American |
| Eddy Navas als Native American |
| Ricky Hawkeye als Native American |
| Pete Dyer als Native American |
| Paul Skyhorse als Native American |
| Gordon Eagle als Native American |
| Javier First-Day-Of-Light als Native American |
| George Stonefish als Native American |
| Julie Evening Lilly als Native American |
| Jane Lind als Native American |
| Annie Gagen als ESS Operator |
| Max Goff als ESS Operator |
| Cullen Johnson als ESS Operator |
| Robert L. King als ESS Operator |
| Robert Moberly als ESS Operator |
 | Caitlin O'Heaney als ESS Operator |
| Tony Stratta als ESS Operator |
| William Sheridan als ESS Operator |
 | Linda Gary als ESS Voice (voice) |
 | Charles Howerton als ESS Voice (voice) (as Charles Howerdton) |
 | Burr DeBenning als ESS Voice (voice) |
 | Corey Burton als ESS Voice (voice) |
 | Patricia Parris als ESS Voice (voice) (as Pat Parris) |
 | Andre Stojka als ESS Voice (voice) |
 | Dan Sturkie als ESS Voice (voice) |
 | Mel Welles als ESS Voice (voice) |
| Diane Bivens als Revolutionary Woman (uncredited) |
| Robert Dahdah als Crowd (uncredited) |
 | Daniel D. Halleck als (uncredited) |
| Angel Ramirez Jr. als Wild Boy (uncredited) |
 | Tom Waits als Drunken Bar Owner (uncredited) |
| Michael Wadleigh | Director |
| David Eyre | Screenplay |
| Whitley Strieber | Novel |
| Michael Wadleigh | Screenplay |
| Alan King | Executive Producer |
| James Horner | Original Music Composer |
| Marshall M. Borden | Editor |
| Martin J. Bram | Editor |
| Dennis Dolan | Editor |
| Chris Lebenzon | Editor |
| Rupert Hitzig | Producer |
| Paul Sylbert | Production Design |
| John Boxer | Costume Design |
| Cis Corman | Casting |
| Sidney Gecker | Script Supervisor |
| Michael Wadleigh | Producer |
| David Chapman | Art Direction |
| Alan Hicks | Set Decoration |
| Eric Roth | Writer |
| Dennis Maitland | Sound Mixer |
| Allen Weisinger | Makeup Artist |
| Carl Fullerton | Special Effects Makeup Artist |
| Frank Bianco | Hairstylist |
| Michael R. Thomas | Special Effects Makeup Artist |
| William C. Gerrity | Unit Production Manager |
| G. Mac Brown | Assistant Production Manager |
| Allan Bromberg | Sound Editor |
| Lon Bender | Sound Effects Editor |
| John Duffy | Sound Effects Editor |
| Stan Gilbert | Sound Effects Editor |
| Robert Grieve | Sound Effects Designer |
| Randy Kelley | Sound Effects Editor |
| Andrew London | Sound Effects Designer |
| Kim Maitland | Sound Recordist |
| Anthony Milch | Sound Effects Editor |
| Bruce Richardson | Sound Effects Editor |
| Marvin Walowitz | Sound Effects Editor |
| Samuel C. Crutcher | Sound Editor |
| Gary A. Hecker | Foley Artist |
| David Eyre | Screenstory |
| Michael Wadleigh | Screenstory |
| Gerry Fisher | Director of Photography |
| Steve Barnett | First Assistant Director |
| Steven Felder | First Assistant Director |
| Alex Hapsas | First Assistant Director |
| Hall Hitzig | Second Assistant Director |
| Rupert Hitzig | Second Unit Director |
| Deborah L. Marrs | Assistant Director Trainee |
| Stephen A. Glanzrock | Second Assistant Director |
| Billy Bishop | Assistant Property Master |
| Edward Garzero | Scenic Artist |
| James Halligan | Construction Grip |
| Richard Hughes | Scenic Artist |
| Herbert F. Mulligan | Set Dresser |
| Carlos Quiles | Carpenter |
| Jimmy Raitt | Property Master |
| Eoin Sprott | Special Props |
| Bobby Wilson | Assistant Property Master |
| Polly Wood-Holland | Scenic Artist |
| George Kousoulides | Scenic Artist |
| Richard M. Kristy | Leadman |
| Richard Shelton | Painter |
| Jay Cassidy | Dialogue Editor |
| James A. Corbett | Sound Re-Recording Mixer |
| Joanne D'Antonio | Dialogue Editor |
| Jill Demby Guest | Dialogue Editor |
| John Fundus | Boom Operator |
| Scott A. Hecker | Foley Editor |
| Charles McCann | Dialogue Editor |
| Michael Minkler | Sound Re-Recording Mixer |
| Ken S. Polk | Sound Re-Recording Mixer |
| John Roesch | Foley Supervisor |
| Robert R. Rutledge | Foley Editor |
| Robert R. Rutledge | Foley Supervisor |
| Burton Weinstein | Dialogue Editor |
| James Bryan | Sound Editor |
| James Horner | Conductor |
| Garrett Brown | Steadycam |
| Fredric Abeles | Director of Photography |
| Chris Hayes | First Assistant Camera |
| Jim Hovey | First Assistant Camera |
| Tom Priestley Jr. | Camera Operator |
| Dan Lerner | Steadicam Operator |
| Ted Churchill | Steadicam Operator |
