 | Sanaa Lathan als Alexa Woods |
 | Raoul Bova als Sebastian de Rosa |
 | Lance Henriksen als Charles Bishop Weyland |
 | Ewen Bremner als Graeme Miller |
 | Colin Salmon als Maxwell Stafford |
 | Tommy Flanagan als Mark Verheiden |
 | Joseph Rye als Joe Connors |
 | Agathe de La Boulaye als Adele Rousseau |
 | Carsten Norgaard als Rusten Quinn |
 | Sam Troughton als Thomas Parks |
 | Petr Jákl als Stone |
 | Pavel Bezděk als Bass |
 | Kieran Bew als Klaus |
 | Carsten Voigt als Mikkel |
 | Jan Filipenský als Boris |
 | Adrian Bouchet als Sven |
 | Andy Lucas als Juan Ramirez |
 | Liz May Brice als Supervisor |
 | Glenn Conroy als Technician |
 | Eoin McCarthy als Karl |
 | Karima McAdams als Sacrificial Maiden |
 | Tom Woodruff Jr. als Grid |
 | Ian Whyte als Scar |
 | Joseph Balderrama als High Priest (uncredited) |
 | Alec Gillis als Technician (uncredited) |
 | Alex Lorre als Spaceship Crew (uncredited) |
 | Jack Pierce als Co-Pilot (uncredited) |
| Paul W. S. Anderson | Director |
| Dan O'Bannon | Screenplay |
| Ronald Shusett | Screenplay |
| Jim Thomas | Author |
| John Thomas | Author |
| Paul W. S. Anderson | Screenplay |
| Gordon Carroll | Producer |
| John Davis | Producer |
| David Giler | Producer |
| Walter Hill | Producer |
| Harald Kloser | Original Music Composer |
| David Johnson | Director of Photography |
| Alexander Berner | Editor |
| Richard Bridgland | Production Design |
| Nancy Bishop | Casting |
| Suzanne Smith | Casting |
| David Minkowski | Co-Producer |
| Matthew Stillman | Co-Producer |
| Ray Chan | Art Direction |
| Stephen Dobric | Art Direction |
| Jindřich Kočí | Art Direction |
| Milena Koubková | Art Direction |
| Justin Warburton-Brown | Art Direction |
| Peter Walpole | Set Decoration |
| Magali Guidasci | Costume Design |
| Adam O'Neill | Supervising Art Director |
| Katerina van Gemundova | Art Department Coordinator |
| Marco Bittner Rosser | Set Designer |
| Stephen Bream | Set Designer |
| Stephan O. Gessler | Set Designer |
| Jan Kodera | Leadman |
| Colin Jackman | Sculptor |
| Simon Gershon | Supervising Sound Editor |
| Jeremy Price | Supervising Sound Editor |
| Melissa Lake | Foley |
| Jason Swanscott | Foley |
| Howard Bargroff | Sound Re-Recording Mixer |
| Simon Gershon | Sound Re-Recording Mixer |
| Andrew Stirk | Sound Re-Recording Mixer |
| Mei-Ming Casino | Visual Effects Producer |
| Ian Differ | Visual Effects Editor |
| Stefan Drury | Visual Effects Producer |
| Angie Wills | Visual Effects Producer |
| Arthur Windus | Visual Effects Producer |
| David Vána | Visual Effects Supervisor |
| Adam Valdez | Visual Effects Supervisor |
| Vít Komrzý | Visual Effects Producer |
| Rick Forsayeth | Stunt Coordinator |
| Jürgen Vollmer | Still Photographer |
| Jaromír Šedina | Steadicam Operator |
| Petr Konrád | Gaffer |
| Jaromír Šedina | Camera Operator |
| John Warhurst | Music Editor |
| Jiri Kotlas | Transportation Coordinator |
| Jessica Clothier | Script Supervisor |
| Andrew Jack | Dialect Coach |
| Lukáš Bech | Location Manager |
| Gabriele Zucchelli | Animation |
| Grace Gilroy | Associate Producer |
| Wyck Godfrey | Executive Producer |
| Thomas M. Hammel | Executive Producer |
| Henning Molfenter | Associate Producer |
| Thierry Potok | Associate Producer |
| Mike Richardson | Executive Producer |
| Chris Symes | Co-Producer |
| Mark Bartholomew | Assistant Art Director |
| Lesley Lamont-Fisher | Hair Designer |
| Ivo Strangmüller | Key Hair Stylist |
| Lesley Lamont-Fisher | Makeup Designer |
| Ivo Strangmüller | Makeup Artist |
| Dawn Dininger | Makeup Effects |
| Barrie Gower | Makeup Effects |
| Simon Webber | Makeup Effects |
| Richard K. Buoen | Conceptual Design |
| Steve Burg | Conceptual Design |
| Jennifer Silver | Line Producer |
| David Selvadurai | Painter |
| Ladislav Hrubý | First Assistant Camera |
| Jiří Gažda | Grip |
| Bára Barová | Set Dressing Supervisor |
| Mattias Lindahl | CG Supervisor |
| Craig Lyn | CGI Supervisor |
| Ben Shepherd | Digital Effects Supervisor |
| Miroslav Čáslavka | Driver |
| Andreas Pense | Legal Services |
| Jason Keever | Post Production Assistant |
| Patrick Esposito | Post-Production Manager |
| Emma Zee | Post Production Supervisor |
| Graham Riddell | Propmaker |
| Robert Milicevic | Security |
| Eva Dvorakova | Set Medic |
| Petra Ratner | Set Production Assistant |
| Michal Holubec | Sound Recordist |
| Jaroslav Peterka | Stunts |
| Adam Goodman | Unit Production Manager |
| Geoff Freeman | Unit Publicist |
| Michal Chadima | Video Assist Operator |
| Charles Ladmiral | First Assistant Editor |
| Martin Tichy | Electrician |
| Rafael Morant | Lighting Artist |
| Dean Brkic | Rigging Gaffer |
| Michal Houzvicka | Rigging Grip |
| Minna Pyyhkala | Casting Associate |
| Mark Birmingham | Production Accountant |
| Claudia Dehmel | Production Coordinator |
| Martina Burgetová | Production Manager |
| Brian Donovan | Production Supervisor |
| Tomáš Červenka | Boom Operator |
| Petr Forejt | Production Sound Mixer |
| Blair Jollands | Sound Editor |
| Mike Grimes | Sound Effects Editor |
| Laurent Cordier | 3D Supervisor |
| Henry Badgett | Digital Compositors |
| Oliver Faldo | I/O Supervisor |
| Karl-Heinz Bochnig | Special Effects Supervisor |
| Charles Howell | Visual Effects Coordinator |
| Lenka Rock | Translator |
| Les Healey | Additional Editing |
| Mark Kenna | Dolby Consultant |
| Stephane Paris | Modeling |
| Jiří Husák | Unit Manager |
| James Seymour Brett | Orchestrator |
| John Bruno | Visual Effects Supervisor |
| Christopher Learmonth | VFX Editor |
| Jitka Švecová | Costumer |
| Radek Petr | Hair Assistant |
| Sherman Hawthorne | Hairdresser |
| Jakub Dvorak | Second Assistant Director |
| Bharat Nalluri | Second Unit Director |
| Lucy Egerton | Third Assistant Director |
| Joseph C. Pepe | Concept Artist |
| Aleksandar Sasha Matic | Draughtsman |
| Craig Cheeseman | Dressing Prop |
| Jan Kotik | Graphic Designer |
| Richard Bennett | Storyboard Artist |
| Miroslav Čáslavka | Swing |
| Nic Benns | Title Designer |
| Gianluca Buttari | ADR Coordinator |
| Marco di Vittorio | ADR Engineer |
| Michael Miller | ADR Mixer |
| Courtney Bishop | ADR Recordist |
| Dan Johnson | Additional Sound Re-Recording Mixer |
| Andrea King | Foley Artist |
| Nigel Bennett | Sound Mix Technician |
| Ian Morgan | Supervising ADR Editor |
| Miriam Ludbrook | Supervising Dialogue Editor |
| Michael Beck | Special Effects Assistant |
| Sam Conway | Special Effects Technician |
| Steven Hall | Visual Effects Camera |
| Rene Hajek | Stunt Double |
| Zdeněk Mrkvička | Assistant Camera |
| Pavel Proisl | Best Boy Grip |
| Václav Kareš | Camera Loader |
| Andrew Baggarley | Data Wrangler |
| Ian Smith | Dolly Grip |
| Karl Morgan | Focus Puller |
| Dan Balzer | Second Assistant Camera |
| Jeremy Lazare | Lead Animator |
| Greg Fisher | Senior Animator |
| Vanessa Baker | ADR Voice Casting |
| Julie Harkin | Casting Assistant |
| Věra Mírová | Wardrobe Master |
| Martin Hubáček | Assistant Editor |
| Brano Danis | Colorist |
| Adam Inglis | Digital Colorist |
| Paul Elman | Digital Intermediate Editor |
| Michael Charles | Negative Cutter |
| Rolf Hanke | Project Manager |
| Karen Elliott | Music Coordinator |
| Andrew Glen | Supervising Music Editor |
| David Trojan | Art Department Production Assistant |
| Karolina Cerna | Assistant Accountant |
| Goran Uljanic | Assistant Production Coordinator |
| Aleksandar Pejic | CG Artist |
| Jirí Hrstka | Extras Casting |
| Renee D. Czarapata | First Assistant Accountant |
| Xavier Roig | Generalist |
| Martin Hobbs | Head of Production |
| Julian Mann | Head of Research |
| Dave Early | Matte Painter |
| Luke Gale | Production Assistant |
| Jan Hogevold | Production Executive |
| Veronika Lencová | Production Secretary |
| Steven Bray | Rotoscoping Artist |
| Marc Marcum | Story Editor |
| James Clarke | Visual Effects |
| Andy Howard | Additional Second Assistant Director |
| Dan O'Bannon | Author |
| Ronald Shusett | Author |
| Ben Meechan | Sound Effects Editor |
| Mark Egerton | First Assistant Director |
| Edward Brett | First Assistant Director |
| Jakub Švec | Stunts |
| Jiri Simberský | Stunts |
| Jan Petřina | Stunts |
| David Motl | Stunts |
| David Lištván | Stunts |
| Angelica Lisk-Hann | Stunt Double |
| Miroslav Lhotka | Stunts |
| Heiko Kiesow | Stunts |
| Petr Hnětkovský | Stunts |
| Michal Grün | Stunts |
| Simon Price | Dialogue Editor |
| H. R. Giger | Creature Design |
| John T. Sweeney | Production Coordinator |
| Noel Cowell | Property Master |
| Dino Herrmann | Technical Advisor |
| Ferran Domenech | Animation |
| Craig Lyn | CG Supervisor |
| Ben Shepherd | Effects Supervisor |
