 | Sandra Bullock als Mary Horowitz |
 | Bradley Cooper als Steve |
 | Thomas Haden Church als Hartman |
 | Ken Jeong als Angus |
 | Katy Mixon als Elizabeth |
 | DJ Qualls als Howard |
 | Keith David als Corbitt |
 | Howard Hesseman als Mr. Horowitz |
 | Beth Grant als Mrs. Horowitz |
 | M.C. Gainey als Norm the Truck Driver |
 | Jason Jones als Vasquez |
 | Carlos Gómez als Rescue Supervisor |
 | Holmes Osborne als Soloman |
 | Delaney Hamilton als Little Deaf Girl |
 | George Sharperson als Rescuer |
 | Luenell als Protestor Lydia |
 | Christina Carlisi als Teacher |
| Joe D'Angerio als ABC News Producer |
| Shanda Laurent als Bus Driver |
 | Kerri Kenney als Miss Hancock |
 | Stephanie Venditto als KNYT Reporter |
 | P.J. Marino als KNYT Sound Tech |
 | Wayne Grace als Retired Mine Supervisor |
 | Mickey Giacomazzi als Skinny Fireman |
 | Noah Munck als Large Kid |
 | Bridget Shergalis als Mini-Mary |
 | James Martin Kelly als Mine Safety Expert |
 | Andrew Lewis Caldwell als Young Rescuer |
| Bryan Moore als Assistant |
 | Rachel Sterling als Booby Botanist |
 | Jackie Johnson als CCN Meteorologist |
| Regino Montes als Maintenance Guy |
 | Elliott Cho als Daniel |
| Justin Grafman als Deaf Boy |
 | Joy Darash als Hipster Girl |
| Jordan Green als Kid |
 | Geraldo Rivera als Self |
 | Beverly Polcyn als Old Lady |
| Misha DiBono als Paula |
| Dori Kancher als Payroll Clerk |
| Vernard 'Bone' Hampton als Security Guard |
 | Hari Kondabolu als Crossword Businessman |
 | Jordan Morris als Protestor Winston |
 | Dorie Barton als Horowitz House Reporter #1 |
| Patrick Brown als Horowitz House Reporter #2 |
| Alvera DeLeon als Horowitz House Reporter #3 |
 | Gillian Vigman als Misc. (Female) News Reporter |
| Michael Joseph Carr als BBC Reporter |
 | Larry Dorf als MSNBC Reporter |
 | Darcy Fowers als Guest Expert |
 | Charlyne Yi als Young Protester |
 | Tyrone Giordano als Dad |
 | Hollie Stenson als Another Reporter |
| Paul Beller als Firefighter |
 | Kurt Ela als Reporter #1 |
 | Kelli Kirkland als Receptionist |
 | Lucy Davis als Patient |
 | Hira Ambrosino als Mrs. Yamamoto (uncredited) |
 | Jonathan Chase als Gregg (uncredited) |
 | Andre Alexsen als Colorado State Trooper (uncredited) |
| Nick Hodaly als CCN Arabic News Anchor (uncredited) |
 | Sara Sanderson als Houston Anchor (uncredited) |
 | Martin Dew als Reporter (uncredited) |
 | Ken Edling als Reporter (uncredited) |
 | Rae Sunshine Lee als Hippie Protester (uncredited) |
| Gregg Lee als Hippie Protester (uncredited) |
| DeeDee Bigelow als Saloon Gal (uncredited) |
| Judy Dinella als Park Bench Girl (uncredited) |
| Rebecca Hyland als Crap Game Stick Woman (uncredited) |
 | Eddie Jemison als Psychiatrist with Crossword Puzzle (uncredited) |
 | Phil Traill als Man at Coffee Shop (uncredited) |
| John Robert als Rescuer (uncredited) |
| Sandra Berry als Cast Worker (uncredited) |
| Phil Traill | Director |
| Kim Barker | Writer |
| Sandra Bullock | Producer |
| Mary McLaglen | Producer |
| Trevor Engelson | Executive Producer |
| Ted Field | Executive Producer |
| Nick Osborne | Executive Producer |
| Christophe Beck | Original Music Composer |
| Juel Bestrop | Casting |
| Seth Yanklewitz | Casting |
| Maher Ahmad | Production Design |
| Tim Suhrstedt | Director of Photography |
| Keii Johnston | Stunts |
| Austin Gorg | Art Direction |
| Angela C. Tortu | First Assistant Director |
| John Tagamolila | Second Assistant Director |
| Gina Bonacquisti | Key Hair Stylist |
| Natasha Ladek | Wigmaker |
| Ann Masterson | Makeup Department Head |
| Sherri Simmons | Makeup Artist |
| Nicole Venables | Hair Department Head |
| Jeffrey Harlacker | Post Production Supervisor |
| Eric Hedayat | Production Supervisor |
| Mary McLaglen | Unit Production Manager |
| Bryan Belair | Construction Coordinator |
| Jonathan Buchanan | Set Dresser |
| Kirk Corwin | Property Master |
| Gretchen Engel | Art Department Coordinator |
| Peter N. Griffith | Assistant Property Master |
| Mark Hunstable | Assistant Art Director |
| Tim Jackson | Construction Foreman |
| Gary Metzen | Painter |
| Jason Vanover | Greensman |
| Ben Woodworth | Painter |
| Eric Bautista | Utility Sound |
| Scott Curtis | Foley Editor |
| Susan Dawes | Dialogue Editor |
| Jonathan Fuh | Boom Operator |
| José Antonio García | Sound Mixer |
| David Giammarco | Sound Re-Recording Mixer |
| Tim Gomillion | Sound Recordist |
| Matthew Harrison | Foley Editor |
| Doug Jackson | Sound Effects Editor |
| David Lucarelli | ADR Recordist |
| Paul Massey | Sound Re-Recording Mixer |
| Dennis Rogers | Sound Recordist |
| Monique 'Nico' Salvato | First Assistant Sound Editor |
| Donald Sylvester | Supervising Sound Editor |
| Johnny Franco III | Special Effects Technician |
| James Reedy | Special Effects Technician |
| Jamie Reedy | Special Effects Technician |
| Shannon J. Thompson | Special Effects Coordinator |
| Nicholas Kim | Visual Effects |
| Emily Wallin | Visual Effects Producer |
| William Mesa | Visual Effects Supervisor |
| Andre Alexsen | Stunts |
| M. James Arnett | Stunt Coordinator |
| Kevin Chase | Stunts |
| Greg Dela Riva | Stunts |
| Tim Drnec | Stunts |
| Gene Hartline | Stunts |
| Michelle Maloney | Stunt Double |
| Kevin Reid | Stunt Double |
| Monty L. Simons | Stunts |
| Matt Bardocz | Best Boy Electric |
| Paul Birk | Rigging Gaffer |
| Michael Duarte | Grip |
| Patrick D. Fields | Grip |
| Paul Goodstein | Key Grip |
| Jesse Gregson | Best Boy Electric |
| Frederick Lawrence | Grip |
| Paul McIlvaine | Gaffer |
| Suzanne Tenner | Still Photographer |
| Anthony J. Kraus | Casting Assistant |
| John McAlary | Casting Assistant |
| Jacquelyn Palmquist | Casting Associate |
| Michele Berumen-Wallin | Casting Associate |
| Jose S. Hernandez | Costumer |
| Gali Noy | Assistant Costume Designer |
| Joey Amron | Editorial Production Assistant |
| Gary Burritt | Negative Cutter |
| Joe Finley | Digital Intermediate Colorist |
| Dale E. Grahn | Color Timer |
| Lara Khachooni | First Assistant Editor |
| Jason Miller | Post Production Coordinator |
| Clint Spillers | Post Production Assistant |
| Jami Philbrick | Post Production Assistant |
| Ralph Coleman | Location Manager |
| Matthew Prisk | Assistant Location Manager |
| Nico Abondolo | Musician |
| Eun-Mee Ahn | Musician |
| Thomas Diener | Musician |
| Daniel DiPrima | Music Editor |
| Matt Fausak | Music Editor |
| Matt Hirt | Musician |
| John Houlihan | Music Supervisor |
| Kevin Kliesch | Orchestrator |
| Darrin McCann | Musician |
| Seda Ozen | Musician |
| Michele Richards | Musician |
| Jeanne E. Skrocki | Musician |
| Casey Stone | Scoring Mixer |
| Marion Tumen | Script Supervisor |
| J. Armin Garza II | Driver |
| Jimmy Ray Pickens | Transportation Captain |
| Chris Raines | Driver |
| Paul E. Stroh | Transportation Coordinator |
| Chad Wadsworth | Driver |
| Tim Whisenant | Driver |
| Terry Woodcock | Driver |
| Bonnie Yamahiro | Driver |
| Richie Adams | Title Designer |
| Alex Betuel | Set Production Assistant |
| John Bocchicchio | Set Medic |
| Robin Brown | Production Secretary |
| Michael DeSantis | Production Accountant |
| Christie Kwan | Assistant Production Coordinator |
| Brigette Lester | Production Coordinator |
| Carol McConnaughey | Unit Publicist |
| Denyse Rossi | Payroll Accountant |
| JoAnn Stevens | Second Assistant Accountant |
| Michelle Stevens | First Assistant Accountant |
| Barbara Harris | ADR Voice Casting |
| Gary Jones | Costume Designer |
| Casey Adams | Stunts |
| Kevin Reid | Stunts |
| Michelle Maloney | Stunts |
| Mike Washlake | Stunts |
| Jim Gill | Stunts |
| Scott Cosgrove | Stunts |
| Donna Evans | Stunts |
| Pat Romano | Stunts |
| Peter Weireter | Stunts |
| Robert L. Stover | Set Decoration Buyer |
| Erik Berentsen | On Set Dresser |
| David Benavides | On Set Dresser |
| James Fernandez | On Set Dresser |
| Ely Vegh | Swing |
| Michael Timman | Swing |
| Michael G. Miller | Swing |
| Eric Kagan | Swing |
| Abraham Vorster | Swing |
| Alexander Belfor | Swing |
| Terry Doherty | Swing |
| Jason Perrine | Art Department Production Assistant |
| John LaBrucherie | Second Second Assistant Director |
| Carlos De La Torre | Second Second Assistant Director |
| Robyn Willey-Pratt | Second Second Assistant Director |
| Jeffrey Greeley | "A" Camera Operator |
| Theda Streetman | First Assistant "A" Camera |
| Rigney Sackley | Second Assistant "A" Camera |
| Thomas Young III | Second Assistant "A" Camera |
| Chris Haarhoff | "B" Camera Operator |
| Chris Haarhoff | Steadicam Operator |
| Zoran Veselic | First Assistant "B" Camera |
| Steven Cueva | Second Assistant "B" Camera |
| Michelle Pizanis | Loader |
| Jeffrey Harlacker | Associate Producer |
| Rod Dean | Editor |
| Hector Corona | Electrician |
| Steve Rollins | Electrician |
| Samantha Bahramian | Electrician |
| Marc L. Gates | Electrician |
| Alan Morier | Electrician |
| Brian Dawson | Electrician |
| Clint J. Borden | Best Boy Grip |
| Carlos M. Gallardo | Dolly Grip |
| Don Duffield | Dolly Grip |
| Jonathan Fischer | Grip |
| Raynee Borchardt | Rigging Grip |
| Joel Randel | Rigging Grip |
| Bruce Ericksen | Costume Supervisor |
| Susan Lichtman | Costumer |
| Robin Borman-Wizan | Costumer |
| Diana Lara | Assistant Location Manager |
| Lara L. Leonard | Actor's Assistant |
| Dori Kancher | Actor's Assistant |
| Lindsey Spaulding | Producer's Assistant |
| Allison Bergstrand | Executive Producer's Assistant |
| Steve Luna | Executive Producer's Assistant |
| Weston Middleton | Actor's Assistant |
| Natalie Truly | Post Production Accountant |
| Rachel Jensen | Set Production Assistant |
| Michelle Maloney | Set Production Assistant |
| Sierra D. Donley | Additional Production Assistant |
| Vicki Goldsmith | Additional Production Assistant |
| Mark Jones | Transportation Co-Captain |
| Richard Wicklund | Studio Teacher |
| Marc C. Geschwind | Extras Casting Coordinator |
| Shawn Williamson | Set Production Assistant |
| Marijan 'Mario' Zoric | Chef |
| Ann Zoric | Assistant Chef |
| Anthony Zoric | Assistant Chef |
| Martin Reyes | Assistant Chef |
| Dave Kasubowski | Craft Service |
| Dan Novy | Visual Effects |
| Toma Bowen | Visual Effects |
| Lincoln Kupchak | Visual Effects |
| Alfred Berger | Visual Effects |
| Ken Stranahan | Visual Effects |
| Don Myers | Visual Effects |
| David Fogg | Visual Effects |
| Alicia Suggs | Visual Effects |
| Jeremy Nelson | Visual Effects |
| John Bavaresco | Visual Effects |
| Simon Coke | Sound Effects Editor |
| David Betancourt | Foley Mixer |
| Charleen Richards-Steeves | ADR Mixer |
| Alicia Stevenson | Foley Artist |
| Dawn Fintor | Foley Artist |
| Zara Park | Digital Intermediate Producer |
| Nick Glennie-Smith | Conductor |
| Kevin Houlihan | Music Coordinator |
| Denis St. Amand | Score Engineer |
| Gene Hartline | Stunt Double |
