 | Whoopi Goldberg als Sarah Mathews |
 | Ted Danson als Hal Jackson |
 | Will Smith als Tea Cake Walters |
 | Nia Long als Zora Mathews |
 | Paul Rodríguez als Jose |
 | Jennifer Tilly als Stacy |
 | Peggy Rea als Alberta |
 | Clyde Kusatsu als Bob Takashima |
 | David Bowe als Teddy |
 | Jeffrey Joseph als James |
 | Rawley Valverde als Diego |
 | Fred Mancuso als Bruce |
 | Charlene Fernetz als Paula |
 | Shawn Levy als Dwayne |
 | Lu Leonard als Sperm Bank Nurse |
| Joe Lerer als Hospital Doctor |
| Janice Edwards als Hospital Nurse |
 | Michael McFall als Hospital Intern |
 | Phyllis Avery als White Woman #1 |
 | Frances Bergen als White Woman #2 |
 | O'Neal Compton als Rocky |
| Michael Halton als Stew |
| William John Murphy als P.A. #1 |
| Ross Benjamin als P.A. #2 |
 | Mel Stewart als Principal Rockwell |
| David E. Kazanjian als Mr. Alden |
| Arnon Milchan | Producer |
| Steven Reuther | Co-Executive Producer |
| Michael Douglas | Producer |
| Mark Isham | Music |
| David R. Ellis | Stunt Coordinator |
| David R. Ellis | Second Unit Director |
| Elizabeth McBride | Costume Designer |
| Hilton Rosemarin | Set Decoration |
| Ellen Heuer | Foley Artist |
| Daniel C. Striepeke | Key Makeup Artist |
| Patrick J. Palmer | Co-Producer |
| Patrick J. Palmer | Second Unit Director |
| Ralf D. Bode | Director of Photography |
| Richard Benjamin | Director |
| Jacqueline Cambas | Editor |
| Evelyn Sakash | Production Design |
| Dawn Swiderski | Assistant Art Director |
| Reuben Cannon | Casting |
| Newt Arnold | First Assistant Director |
| Marcia Brandwynne | Screenplay |
| Marcia Brandwynne | Executive Producer |
| Nadine Schiff | Screenplay |
| Nadine Schiff | Executive Producer |
| Holly Goldberg Sloan | Screenplay |
| Rick Bieber | Producer |
| Ted Churchill | Steadicam Operator |
| Eileen Sieff Stroup | Costume Supervisor |
| Dean Backer | Assistant Property Master |
| Dick Ziker | Stunts |
| Barbara Harris | ADR Voice Casting |
| Kristen Ross | Art Department Coordinator |
| Susan Germaine | Hairstylist |
| Paul Martinez | Assistant Editor |
| Lester Wilson | Choreographer |
| Lester Wilson | In Memory Of |
| Christopher T. Welch | Sound Editor |
| Robin Harlan | Foley Artist |
| Joe M. Aguilar | Unit Production Manager |
| Robert 'Bobby Z' Zajonc | Pilot |
| Michael Germain | Key Makeup Artist |
| Richard Whitfield | Music Editor |
| Pamela Alch | Script Supervisor |
| Sarah Monat | Foley Artist |
| Chris Jenkins | Sound Re-Recording Mixer |
| Mark Gordon | Sound Editor |
| Doug Hemphill | Sound Re-Recording Mixer |
| Alan Collis | Transportation Coordinator |
| Don Miloyevich | Property Master |
| Zade Rosenthal | Still Photographer |
| Mary Elizabeth Still | Costumer |
| Candace Neal | Hairstylist |
| Rodney Armanino | Construction Coordinator |
| Richard Reseigne | Construction Coordinator |
| Gregory J. Barnett | Stunts |
| Joe Everett | Unit Publicist |
| Richard Lightstone | Sound Mixer |
| Julia L. Walker | Key Hair Stylist |
| Jeff Mart | Steadicam Operator |
| Seven McDonald | Production Assistant |
| Peter Gulla | First Assistant Camera |
| Harald Ortenburger | Camera Operator |
| Dick Rudolph | Music Supervisor |
| Mark Smith | Sound Re-Recording Mixer |
| L. Dean Jones Jr. | First Assistant Director |
| Robin Lynn Bonaccorsi | Stunts |
| Jeff Bushelman | Supervising Sound Editor |
| Stan McClain | Aerial Director of Photography |
| David Giella | Casting Associate |
| Richard M. Ellis | Stunts |
| Paul Bode | Second Assistant Camera |
| Mike Dobie | Supervising Sound Editor |
| Richard D. Montoya | Choreographer |
| Brian Jay | Production Assistant |
| Donah Bassett | Negative Cutter |
| Ida Lee Henderson | Production Accountant |
| Don Weinger | Assistant Art Director |
| George F. Mauricio | Set Dresser |
| Peter C. Barbour | Sound Editor |
| Scott Burrow | Sound Editor |
| Margaret Adachi | Assistant Editor |
| Charles Miller | Location Manager |
| Don Watson | Leadman |
| Tom Sindicich | Special Effects |
| Gregory M. Childers | Electrician |
| Kathy Sarreal | Production Coordinator |
| Steve Cardellini | Dolly Grip |
| Frank Strzalkowski | Gaffer |
| Christina Tucker | ADR Mixer |
| Amanda Chamberlin | Costumer |
| Michael Becker | Costumer |
| Carol Dantuono | Post Production Supervisor |
| Christopher Desmond | Set Medic |
| Hillary Murray | Color Timer |
| Bruce Bell | Foley Mixer |
| Raquel Osborne | Extras Casting |
| Nathan Gendzier | Location Manager |
| Bryan Denegal | Second Assistant Director |
| Barbara Hartman-Jenichen | Costumer |
| Jay Roberts | Assistant Accountant |
| Chris H. Kelly | Construction Coordinator |
| John A. Small | Second Assistant Camera |
| Gary Gill | Best Boy Grip |
| Joe Carl Parsons | Best Boy Electric |
| Duke Brown | Sound Editor |
| Suzanne Rothbaum | Associate Producer |
| Diane Seniw | Assistant Accountant |
| Heidi McGuire | Assistant Production Coordinator |
| Erin Fiedler | Production Secretary |
| Debra A. Girard | Location Manager |
| Richard Brodsky | Second Second Assistant Director |
| Eugene M. Texeira | Set Dresser |
| Ray Mondoux | Construction Foreman |
| Jon Guterres | Key Grip |
| Jeff Gilliam | Rigging Grip |
| Wesley Riley | Grip |
| Charma Ferreira | Grip |
| Curt Cabral | Electrician |
| Andrea Kahn | Electrician |
| Gary Dowling | Boom Operator |
| Robert A. Corso | Props |
| Joseph A. Ruzecki | Production Assistant |
| Natalia Matthews | Production Assistant |
| Brian Hofstetter | Production Assistant |
| Oscar Briones | Production Assistant |
| Kevin F. Walsh | Production Assistant |
| Rick Rozzini | Choreographer |
| Chick Elwell | Transportation Captain |
| Timothy C. Dobie | Assistant Sound Editor |
| Debbie Peterson | Assistant Sound Editor |
| James J. Wilhelm | Craft Service |
