 | Jared Leto als Dr. Michael Morbius / Morbius |
 | Matt Smith als Milo / Lucien |
 | Adria Arjona als Martine Bancroft |
 | Jared Harris als Dr. Emil Nicholas |
 | Al Madrigal als Agent Alberto Rodriguez |
 | Tyrese Gibson als Agent Simon Stroud |
 | Michael Keaton als Adrian Toomes / Vulture |
 | Charlie Shotwell als Young Michael |
 | Bern Collaço als NYPD Police Officer |
 | Tina Louise Owens als Nobel Prize Gown Guest |
 | Tom Forbes als Finance Bro |
 | Amanda Perez als Reporter #4 |
 | Archie Renaux als Bobby |
 | Abraham Popoola als Ryan |
 | Corey Johnson als Mr. Fox |
 | Crystal Wingx als Nobel Prize Gown Guest |
 | Ruth Horrocks als Diner Customer |
 | Kadrolsha Ona Carole als Nobel Prize Guest |
 | Clara Rosager als Jean |
 | Barry Aird als Newspaper Vendor |
| Colin Blyth als Nobel Prize Tuxedo Guest |
 | Gloria García als Martine's Mother |
 | Bentley Kalu als Private Security Professional #2 |
 | Atul Sharma als Nobel Prize Tuxedo Guest |
 | Dave Simon als Nobel Prize official |
 | Kalle Hennie als Norwegian Bodyguard |
 | Adam El Hagar als NYPD Cop #2 |
| Chris Ryman als Officer Dyson |
 | Manoj Anand als Nobel Prize Tuxedo Guest |
| Nick Owenford als Nobel Prize Tuxedo Guest |
 | George Symmans als morbhead |
| Pietro Scalia | Editor |
| Avi Arad | Producer |
| Oliver Wood | Director of Photography |
| Lucas Foster | Producer |
| Per Hallberg | Supervising Sound Editor |
| Tina Jones | Set Decoration |
| Cindy Evans | Costume Design |
| Louise Rosner-Meyer | Executive Producer |
| Paul Massey | Sound Re-Recording Mixer |
| Stefania Cella | Production Design |
| Daniel Espinosa | Director |
| Roy Thomas | Characters |
| Beau Borders | Sound Re-Recording Mixer |
| Matt Tolmach | Producer |
| James Lewis | Art Direction |
| Jon Ekstrand | Original Music Composer |
| Matt Sazama | Screenplay |
| Matt Sazama | Screenstory |
| Burk Sharpless | Screenplay |
| Burk Sharpless | Screenstory |
| Emma Ludbrook | Executive Producer |
| Joseph DiValerio | VFX Artist |
| Ann Scibelli | Sound Designer |
| Gary Powell | Stunt Coordinator |
| Travis Baumann | VFX Artist |
| Shamim Seifzadeh | Set Designer |
| Joel Behrens | Visual Effects Supervisor |
| Randy Torres | Sound Designer |
| Gil Kane | Characters |
| Victoria Keeling | Visual Effects Producer |
| Jane Harwood | Assistant Art Director |
| Eric Kimelton | Visual Effects Producer |
| Yoshi DeHerrera | Visual Effects Supervisor |
| Jakob Lundbye | VFX Artist |
| Matt Gendron | Art Direction |
| Louise Young | Makeup Artist |
| Holly Freeman | Costume Supervisor |
| Fred M. Ortiz | Set Dresser |
| Louis Mackall | Visual Effects Supervisor |
