 | Gene Hackman als Lex Luthor |
 | Christopher Reeve als Clark Kent / Superman |
 | Marlon Brando als Jor-El |
 | Ned Beatty als Otis |
 | Jackie Cooper als Perry White |
 | Sarah Douglas als Ursa |
 | Margot Kidder als Lois Lane |
 | Jack O'Halloran als Non |
 | Valerie Perrine als Eve Teschmacher |
 | Clifton James als Sheriff |
 | E.G. Marshall als The President |
 | Marc McClure als Jimmy Olsen |
 | Terence Stamp als General Zod |
 | John Ratzenberger als Controller #1 |
 | Gordon Rollings als Fisherman |
 | Angus MacInnes als Prison Warden |
 | Richard LeParmentier als Reporter |
 | Don Fellows als General |
 | Michael Shannon als President's Aide |
 | Tony Sibbald als Presidential Imposter |
 | Tommy Duggan als Diner Owner |
| Pamela Mandell als Waitress |
 | Pepper Martin als Rocky |
 | Shane Rimmer als Controller #2 |
 | Richard Donner als Man Walking by Diner (uncredited) |
| Cleon Spencer als Kid #1 |
| Carl Parris als Kid #2 |
 | Matt Kaminsky als Looping Christopher Reeve |
| Austin Majors als Ranch Boy (voice) |
 | Aaron Smolinski als Baby Kal-El |
| Maxwell Craig als Prison Inmate (uncredited) |
| Richard Donner | Director |
| Christopher Ivins | Compositing Artist |
| Barbara Anne Klein | Stunt Double |
| Christine Dougherty | Digital Intermediate Producer |
| Robert Paynter | Director of Photography |
| Peter MacDonald | Camera Operator |
| Randy Kelley | Sound Effects Editor |
| Adam Avitabile | Visual Effects |
| Chad Buehler | Digital Compositor |
| Mario Puzo | Story |
| Clay Sparks | Visual Effects |
| Peter Howitt | Set Decoration |
| Maurice Fowler | Supervising Art Director |
| Freddie Cooper | Camera Operator |
| Troy Porter | ADR Mixer |
| Jay Duerr | Music Editor |
| Leslie Newman | Screenplay |
| Debbie McWilliams | Casting |
| Geoffrey Helman | Production Manager |
| Andy Armstrong | Second Unit Director |
| Anthony Racco | Matte Painter |
| Peter Murton | Production Design |
| Ai-Ling Lee | Sound Effects Editor |
| Edward M. Steidele | Foley Artist |
| Chris Trent | Foley Mixer |
| Ilya Salkind | Executive Producer |
| Pierre Spengler | Producer |
| Allan James | Unit Manager |
| Peter Young | Set Decoration |
| John Morgan | Camera Operator |
| Kelly Cabral | Supervising Sound Editor |
| Cameron Frankley | Sound Designer |
| Jenny Foster | Visual Effects Producer |
| Ginger Gemmel | Camera Operator |
| Sue Yelland | Costume Design |
| John Williams | Original Music Composer |
| Jerry Trent | Foley Artist |
| Gregory H. Watkins | Other |
| Ken Thorne | Additional Music |
| Michael Kaelin | Digital Compositor |
| Tim LeBlanc | Other |
| Michael Crawford | Executive In Charge Of Production |
| Cornelia Magas | Digital Compositor |
| Charles Bishop | Art Direction |
| David Garfath | Camera Operator |
| David Wynn-Jones | Focus Puller |
| Eric Tomlinson | Music Sound Design and Processing |
| Maurice Gillett | Gaffer |
| Jerry Siegel | Characters |
| Lynn Stalmaster | Casting |
| Anthony 'Max' Ivins | Visual Effects Supervisor |
| Kurt Bryant | Stunts |
| Barbara Anne Klein | Stunt Coordinator |
| Norman Reynolds | Art Direction |
| Terry Ackland-Snow | Art Direction |
| David Wynn-Jones | First Assistant Camera |
| Stuart Baird | Editor |
| Jon Michaels | Assistant Sound Editor |
| Vincent Winter | Production Manager |
| Charles F. Greenlaw | Associate Producer |
| Kevin R. Browne | Visual Effects |
| Denys N. Coop | Other |
| Paul Wilson | Other |
| Michele Tandy | Assistant Accountant |
| Rebecca Ramsey | Visual Effects Producer |
| Gabriel Sánchez | Visual Effects |
| Ernest Archer | Art Direction |
| Yvonne Blake | Costume Design |
| Michael Thau | Editor |
| Colin Chilvers | Special Effects Supervisor |
| Derek Hoffman | Co-Producer |
| Denis Rich | Storyboard Artist |
| Michael Collins | Digital Compositor |
| Rob Ozaeta | Visual Effects |
| Chic Waterson | Camera Operator |
| Tom Mankiewicz | Creative Consultant |
| Joe Shuster | Characters |
| David Newman | Screenplay |
| Mario Puzo | Screenplay |
| Maria Monreal | Other |
| Douglas Noakes | Production Accountant |
| Cecil F. Ford | Production Supervisor |
| Michael Thau | Producer |
| Brian Christensen | Stunts |
| Marc Fisher | Editorial Staff |
| John Harris | Camera Operator |
| Stuart Freeborn | Makeup Artist |
| John Victor-Smith | Editor |
| Roy Field | Visual Effects Supervisor |
| Melissa A. Corns | Assistant Sound Editor |
| Derek Bird | Digital Compositor |
| Mark Driscoll | Visual Effects Producer |
| Tim Hampton | Production Supervisor |
| Danny S. Kim | Visual Effects Art Director |
| John Barry | Production Design |
| Geoffrey Unsworth | Director of Photography |
| Zoran Perisic | Special Effects Supervisor |
| Cyntia Büll | Digital Compositor |
| Frans J. Afman | Finance |
| Felix Ojeda | Digital Compositor |
| Lloyd Lee Barnett | Digital Compositor |
| Robert Simmonds | Production Manager |
| Michael Kennen | Digital Compositor |
