 | Ryan Reynolds als Wade Wilson / Deadpool |
 | Morena Baccarin als Vanessa |
 | Ed Skrein als Ajax |
 | T.J. Miller als Weasel |
 | Gina Carano als Angel Dust |
 | Leslie Uggams als Blind Al |
 | Brianna Hildebrand als Negasonic Teenage Warhead |
 | Karan Soni als Dopinder |
 | Jed Rees als Recruiter |
 | Stefan Kapičić als Colossus (voice) |
 | Randal Reeder als Buck |
 | Isaac C. Singleton Jr. als Boothe |
 | Michael Benyaer als Warlord |
 | Style Dayne als Jeremy (Pizza Guy) |
 | Kyle Cassie als Gavin Merchant |
 | Taylor Hickson als Meghan Orlovsky |
 | Ayzee als Teen Girl #1 |
 | Naika Toussaint als Teen Girl #2 |
 | Justyn Shippelt als Arcade Ticket Taker |
 | Donna Yamamoto als Oncologist |
 | Hugh Scott als David Cunningham |
 | Cindy Piper als Chinatown Merchant |
 | Em Haine als Whisper Girlfriend |
 | Aatash Amir als Whisper Boyfriend |
 | Chad Riley als Pool Hall Goon |
 | Paul Belsito als Fight Club Boss |
 | Darcey Johnson als Garbage Truck Driver |
 | Kyle Rideout als Super Soldier #1 |
 | Jason William Day als Super Soldier #2 |
 | Stan Lee als Strip Club DJ |
 | Benjamin Wilkinson als No5 Orange Manager |
 | Rachel Sheen als Strip Club Worker |
 | Paul Lazenby als Flight Deck Guard |
 | Rob Hayter als Bob |
 | Andre Tricoteux als On-Set Colossus (uncredited) |
 | Victoria De Mare als Stripper (uncredited) |
 | Heather Ashley Chase als Stripclub Pole Performer (uncredited) |
 | Kayla Adams als Waitress Kelly (uncredited) |
 | Olesia Shewchuk als Guadalajaran Mother (uncredited) |
 | Fabiola Colmenero als Guadalajaran Nurse (uncredited) |
 | Matthew Hoglie als Strip Club Patron (uncredited) |
| Robert Alonzo | Stunt Coordinator |
| Tim Miller | Director |
| Sala Baker | Stunts |
| Ryan Reynolds | Producer |
| Simon Kinberg | Producer |
| Lauren Shuler Donner | Producer |
| Ken Seng | Director of Photography |
| Julian Clarke | Editor |
| Ronna Kress | Casting |
| Corinne Clark | Casting |
| Jennifer Page | Casting |
| Hannah d'Angerio | Casting Associate |
| Greg Berry | Art Direction |
| Teresa Ngan | Art Department Coordinator |
| Marc Aubin | Art Department Assistant |
| Sean Haworth | Production Design |
| Shannon Gottlieb | Set Decoration |
| Angus Strathie | Costume Design |
| Michael Mew | Assistant Costume Designer |
| Erin da Roza | Set Costumer |
| Silke Guglielmo | Set Costumer |
| Amy Schilbe | Set Costumer |
| Bill Corso | Makeup Designer |
| Rob Fournier | Armorer |
| Ric Walkington | Armorer |
| Ted Caplan | Music Editor |
| John Houlihan | Music Supervisor |
| Dean Heselden | Camera Operator |
| Stephen Maier | Camera Operator |
| Sasha Proctor | Camera Operator |
| Mark Cohen | Camera Operator |
| Richard Roles | Helicopter Camera |
| Norbert Kaluza | Steadicam Operator |
| Joseph Lederer | Still Photographer |
| David Dolsen | Still Photographer |
| Andrew W. Davidson | Gaffer |
| Burton 'Joe' Kuchera | Gaffer |
| Keith Woods | Rigging Gaffer |
| Adam Bunz | Rigging Grip |
| Herb DeWaal | Rigging Grip |
| Daryl Makortoff | Rigging Grip |
| Ai-Ling Lee | Sound Designer |
| Craig Henighan | Sound Designer |
| Warren Hendriks | Sound Designer |
| Benjamin Beardwood | Sound Editor |
| Will Files | Sound Re-Recording Mixer |
| Paul Massey | Sound Re-Recording Mixer |
| Jim Brookshire | Supervising Sound Editor |
| Warren Hendriks | Supervising Sound Editor |
| Wayne Lemmer | Supervising Sound Editor |
| Shaun Friedberg | Animation Director |
| Jan Philip Cramer | Animation Director |
| Pimentel A. Raphael | Animation Supervisor |
| Alex Burdett | Special Effects Supervisor |
| Luke Botteron | VFX Editor |
| Matthew G. Carson | First Assistant Editor |
| Teresa Berus | Visual Effects Coordinator |
| Patrick Thomas O'Rourke | Visual Effects Coordinator |
| Tamar Shaham | Visual Effects Coordinator |
| Sammy Shikaze | Visual Effects Coordinator |
| Brittany Montero | Visual Effects Coordinator |
| Dipankar Sarkar | Visual Effects Coordinator |
| Tim Weber | Visual Effects Coordinator |
| Cole Darby | Visual Effects Coordinator |
| Sara Bourque | Visual Effects Coordinator |
| Thibaud Galbois | Visual Effects Coordinator |
| Paul Wernick | Executive Producer |
| Rochelle Okoye | Stunts |
| Krista Bell | Stunts |
| Amy Johnston | Stunts |
| Atlin Mitchell | Stunts |
| Wayne Dalglish | Stunts |
| Nevin Swain | Property Master |
| Tim Gomillion | Sound Recordist |
| Laura Graham | ADR Editor |
| Tom Holkenborg | Original Music Composer |
| Susan Dawes | Supervising Dialogue Editor |
| Teri E. Dorman | Dialogue Editor |
| Stan Lee | Executive Producer |
| John J. Kelly | Executive Producer |
| Jonathon Komack Martin | Executive Producer |
| Rhett Reese | Executive Producer |
| Aditya Sood | Executive Producer |
| Thane Watkins | Associate Producer |
| Natasha Denis | Stunts |
| David Goyer | Generator Operator |
| Thom MacIntyre | Assistant Hairstylist |
| Brittany Fontaine | Assistant Makeup Artist |
| Sven Granlund | Assistant Makeup Artist |
| Neal Kennemore | Assistant Makeup Artist |
| David Dupuis | Assistant Makeup Artist |
| Richard Alonzo | Assistant Makeup Artist |
| Diane Holme | First Assistant Hairstylist |
| Beth Boxall | First Assistant Makeup Artist |
| Ailsa Macmillan | Hairstylist |
| Danna Rutherford | Hairstylist |
| Anne Carroll | Hair Department Head |
| Monica Huppert | Makeup Department Head |
| Tanya Hudson | Key Makeup Artist |
| Cindy L. Larsen | Makeup Artist |
| Geoff Redknap | Prosthetic Makeup Artist |
| Mike Fields | Prosthetic Makeup Artist |
| Andy Clement | Prosthetic Designer |
| Holland Miller | Special Effects Makeup Artist |
| Briana Scott | Ager/Dyer |
| Kurtis Reeves | Costume Coordinator |
| Susan O'Hara | Costume Set Supervisor |
| Koreen Heaver | Costumer |
| Roma Wnuk | Seamstress |
| Cat Mudryk | Set Costumer |
| Michael Tamayo | Set Costumer |
| Andre Brouwer | Truck Supervisor |
| Rob Brady | Best Boy Electric |
| Mike Hrycan | Best Boy Grip |
| Colin Robson | Best Boy Grip |
| Mitch Bax | Digital Imaging Technician |
| Chris Bolton | Digital Imaging Technician |
| Luke T. Campbell | Digital Imaging Technician |
| Clark Birchmeier | Digital Imaging Technician |
| Roger Vernon | Second Unit Director of Photography |
| Gil Forrester | Dolly Grip |
| Nicholas Dent | Dolly Grip |
| Damien Giles | Dolly Grip |
| Stu Carl | Dolly Grip |
| Kai Lydgate | Electrician |
| Alex Montano | Electrician |
| Christian Schauz | Electrician |
| Jason Tidsbury | Electrician |
| Doug Lavender | First Assistant "A" Camera |
| Kieran Humphries | First Assistant "B" Camera |
| Jeff Sayle | First Assistant "C" Camera |
| James Claire | First Assistant "D" Camera |
| Sean Elliott | First Assistant Camera |
| Justin Bergler | First Assistant Camera |
| Julian Chapdelaine | Grip |
| Marco Correia | Grip |
| Obedi Daniel | Grip |
| Miguel Gelinas | Grip |
| Kyle Hou | Grip |
| Jon Jovellanos | Grip |
| Shane Kjar | Grip |
| Kevin Lheritier | Grip |
| Denis Marcotte | Grip |
| Shane Nasmith | Grip |
| Milton Ng | Grip |
| Marc Nolet | Grip |
| Jesse D.E. Young | Grip |
| Charles Koetke | Grip |
| Finn King | Key Grip |
| Josh Holmes | Lighting Technician |
| Richard MacDonald | Lighting Technician |
| Matty Reed | Lighting Technician |
| Ronald Richard | Lighting Technician |
| Tony Richardson | Lighting Technician |
| Trevor Steeves | Lighting Technician |
| Laura May Taylor | Lighting Technician |
| Chris Unsworth | Lighting Technician |
| Robin West | Lighting Technician |
| Danielle Bowerbank | Rigging Grip |
| Chris Cristobal | Rigging Grip |
| Ian Gariepy | Rigging Grip |
| Jeremy Goodrick | Rigging Grip |
| Andrew Kearney | Rigging Grip |
| Adrian Netto | Rigging Grip |
| Alex Reno | Rigging Grip |
| Dan Morrison | Second Assistant "A" Camera |
| Salomon Saade | Second Assistant "A" Camera |
| Joshua Marcoux | Second Assistant "B" Camera |
| Rodrigo Carcamo Parga | Second Assistant "B" Camera |
| Sean Cooke | Second Assistant "C" Camera |
| Scott Cozens | Second Assistant "D" Camera |
| Spencer Ennis | Second Assistant Camera |
| Jordon Baker | Second Assistant Camera |
| Preston Cook | Second Assistant Camera |
| Michael Grant | Second Assistant Camera |
| James Bitonti | First Assistant Director |
| Bryan Goeres | First Assistant Director |
| David Klohn | First Assistant Director |
| Dan Mansfield | Second Assistant Director |
| Eddy Santos | Second Assistant Director |
| Robert Alonzo | Second Unit Director |
| Benjamin Cairns | Third Assistant Director |
| Rhonda Taylor | Third Assistant Director |
| Karin Behrenz | Third Assistant Director |
| Scott Kukurudz | Third Assistant Director |
| Susan Lambie | Script Supervisor |
| Damon Bebee | Assistant Property Master |
| Ina Brooks | Assistant Property Master |
| Jerry Staar | Assistant Property Master |
| Zoe Jirik | Assistant Set Decoration |
| Marty Adamski | Carpenter |
| Jason Dampier | Carpenter |
| Richard Elder | Carpenter |
| Mario A. Jones | Carpenter |
| Clive Joslin | Carpenter |
| Richard Tremblay | Carpenter |
| James Paick | Concept Artist |
| Emmanuel Shiu | Concept Artist |
| Josue Clotaire Fleurimond | Conceptual Illustrator |
| Jesse Joslin | Construction Coordinator |
| Hugo Mallory | Construction Foreman |
| Dylan Dowd | Head Greensman |
| Sally Hudson | Graphic Designer |
| Keej Mullen | Property Buyer |
| D. Martin Myatt | Property Master |
| Fiorino Corsi | Props |
| Paul Wagner | Props |
| Miho Yamamoto | Props |
| Randy Hutniak | Set Designer |
| Sheila Millar | Set Designer |
| Sean Blackie | Set Dresser |
| Molly Carney | Set Dresser |
| Kelly McLeod | Set Dresser |
| Kelly Santbergen | Set Dresser |
| Rachel Terry | Set Dresser |
| Leah Wiebe | Set Dresser |
| Matthew L. Eisenhauer | Standby Carpenter |
| Alexander Lozano | Storyboard Artist |
| Jay Oliva | Storyboard Artist |
| Nigel Evans | Supervising Art Director |
| Craig Henighan | Additional Sound Re-Recording Mixer |
| R.J. Kizer | ADR Editor |
| Derek Casari | ADR Engineer |
| David Betancourt | ADR Mixer |
| Max Greene | ADR Mixer |
| Andy Stallabrass | ADR Mixer |
| Charleen Richards-Steeves | ADR Mixer |
| Chris Chae | ADR Recordist |
| David Lucarelli | ADR Recordist |
| Jay Shilliday | ADR Recordist |
| Millar Montgomery | Boom Operator |
| Tysen Schieber | Boom Operator |
| Skip Longfellow | First Assistant Sound Editor |
| John T. Cucci | Foley Artist |
| Dan O'Connell | Foley Artist |
| Matthew Harrison | Foley Editor |
| James Ashwill | Foley Mixer |
| Blake Collins | Foley Mixer |
| Jack Cucci | Foley Mixer |
| Roberto Dominguez Alegria | Foley Mixer |
| David Husby | Production Sound Mixer |
| Juniper Watters | Sound Assistant |
| Wayne Lemmer | Sound Designer |
| Michelle Gold | Assistant Editor |
| Brian Zwiener | Assistant Editor |
| Jaan Spirka | Colorist |
| Tim Stipan | Digital Intermediate Colorist |
| Amy Pawlowski | Digital Intermediate Editor |
| Vashi Nedomansky | Editorial Consultant |
| Steve Gray | Pilot |
| Alexandre Cancado | 2D Supervisor |
| Benoit Bourgoin | 3D Generalist |
| Lenora Acidera | 3D Generalist |
| Jonathan Fleming-Bock | CG Artist |
| Jason Funk | CG Artist |
| Andy Martinez Calzadilla | CG Artist |
| Jorge de Jesús Pérez Alba | CG Artist |
| David 'Rudy' Grossman | CG Supervisor |
| Laurent Taillefer | CG Supervisor |
| Sebastien Chort | CG Supervisor |
| Pavel Pranevsky | CG Supervisor |
| Oded Raz | CG Supervisor |
| Richard Sutherland | CG Supervisor |
| Andrew Zink | CG Supervisor |
| Carlos Anaya | CG Supervisor |
| Thomas Hullin | CG Supervisor |
| Wesley Cronk | Compositing Lead |
| Mark Casey | Compositing Supervisor |
| Ben Morgan | Compositing Supervisor |
| Woei Lee | Compositing Supervisor |
| Shervin Shoghian | Compositing Supervisor |
| Natalia de la Garza | Compositing Supervisor |
| Martin Lipmann | Compositing Supervisor |
| Sean Heuston | Compositing Supervisor |
| Andrew Shanks | Compositor |
| Patrick Louie | Compositor |
| Rowan Young | Compositor |
| John Brennick | Compositor |
| Brian Fortune | Compositor |
| Joseph Silva | Compositor |
| Yvonne Oh | Compositor |
| Garrett Wycoff | Compositor |
| Michael Yates | Compositor |
| Ravi Deula | Compositor |
| Kory Juul | Compositor |
| Daniel Luke Orr | Compositor |
| Troy Ramsey | Compositor |
| Sören Volz | Compositor |
| Reuben Barkataki | Digital Compositor |
| Tadeusz Chmiel | Digital Compositor |
| Jeremy Ezekiel | Digital Compositor |
| Jérôme Foucout | Digital Compositor |
| Carlos Guillén | Digital Compositor |
| Marie-Ève Gélinas | Digital Compositor |
| Julien Hery | Digital Compositor |
| Julien Klein | Digital Compositor |
| Eric Larivée | Digital Compositor |
| Trevor Moniz | Digital Compositor |
| Christian Morin | Digital Compositor |
| Nguon Vissal Ong | Digital Compositor |
| George Wharton | Digital Compositor |
| Juan Fermin Maldonado | Digital Compositor |
| Paul George Palop | Digital Effects Supervisor |
| Justin Johnson | Digital Effects Supervisor |
| Nick Booth | Digital Effects Supervisor |
| David Larochelle | Compositing Lead |
| James Waterson | Compositing Lead |
| Mark Joey Tang | Compositing Lead |
| Frankie Stellato | Lead Animator |
| Kerry Graham | VFX Lighting Artist |
| Karen E.M. Hulse | VFX Lighting Artist |
| Vladimir Isailovic | VFX Lighting Artist |
| Biagio Figliuzzi | VFX Lighting Artist |
| Ryan Duhaime | VFX Lighting Artist |
| Samuel Jacques | VFX Lighting Artist |
| Veronique Levesque | VFX Lighting Artist |
| Jin Yong Kim | Matchmove Supervisor |
| Marc Jones | Matchmove Supervisor |
| Etienne Poulin St-Laurent | Matchmove Supervisor |
| Heather Abels | Matte Painter |
| Francine Almeida | Matte Painter |
| Nicolas Donel | Matte Painter |
| Francois Croteau | Matte Painter |
| Éric Hamel | Matte Painter |
| Dhamindra Jeevan | Matte Painter |
| Kui Han Lee | Modeling |
| Julien Dubuisson | Pipeline Technical Director |
| Alan Fregtman | Pipeline Technical Director |
| Marie Fétiveau | Pipeline Technical Director |
| Laura Kwan | Pipeline Technical Director |
| Amaury Matu | Pipeline Technical Director |
| Jean-Christophe Morin | Pipeline Technical Director |
| Jordi Riera | Pipeline Technical Director |
| Carine Touraille | Pipeline Technical Director |
| Adam Wierzchowski | Pipeline Technical Director |
| Amirah Busairi | Rotoscoping Artist |
| Gabriel Giguère | Rotoscoping Artist |
| Katie Williams | Rotoscoping Artist |
| Linda Y. Kim | Rotoscoping Artist |
| Rob MacBride | Rotoscoping Artist |
| Gareth Thomas | Rotoscoping Artist |
| Tarquin Vosper | Rotoscoping Artist |
| Bryan Vizcaya | Roto Supervisor |
| Stephen A. Buckley | Senior Animator |
| Allen Holbrook | Senior Animator |
| Brad Lincoln | Senior Animator |
| Jonathan Macintosh | Senior Animator |
| Keith W. Smith | Senior Animator |
| Anto Juricic | Senior Modeller |
| Neil Greenberg | VFX Editor |
| Abhishek Chauhan | VFX Editor |
| Arvind Chaurasiya | VFX Editor |
| Omkar Iyer | VFX Editor |
| Abraham Thomas | VFX Editor |
| Guillaume Poulin | VFX Editor |
| Neil Mayo | VFX Editor |
| Kumar Gaurav | Visual Effects Producer |
| Annemarie Griggs | Visual Effects Producer |
| Roopesh Gujar | Visual Effects Producer |
| Abbigail Keller | Visual Effects Producer |
| Abhishek Kumar | Visual Effects Producer |
| Ravindra Tamhankar | Visual Effects Producer |
| Erika Abrams | Visual Effects Producer |
| Devin Fairbairn | Visual Effects Producer |
| Robin L. D'Arcy | Visual Effects Producer |
| Annie Cliche | Visual Effects Producer |
| Martin Wiseman | Visual Effects Producer |
| Philippe Bienvenue | Visual Effects Production Assistant |
| Ève Giordani | Visual Effects Production Assistant |
| Sarah Elizabeth Howe | Visual Effects Production Assistant |
| Catherine Maillette | Visual Effects Production Assistant |
| Melanie Murray | Visual Effects Production Assistant |
| Marc-André Roy | Visual Effects Production Assistant |
| Darnie Galloway | Visual Effects Production Manager |
| Marie-Ève Authier | Visual Effects Production Manager |
| Julie Kubbillun | Visual Effects Production Manager |
| Tom Greene | Visual Effects Production Manager |
| Jonathan Rothbart | Visual Effects Supervisor |
| Pankaj Sonawane | Visual Effects Supervisor |
| Ryan Tudhope | Visual Effects Supervisor |
| Pauline Duvall | Visual Effects Supervisor |
| Alex Wang | Visual Effects Supervisor |
| Vincent Cirelli | Visual Effects Supervisor |
| Charlie Iturriaga | Visual Effects Supervisor |
| Wayne Brinton | Visual Effects Supervisor |
| Blaine Lougheed | Visual Effects Supervisor |
| Charles Tait | Visual Effects Supervisor |
| Luis Barquero | VFX Artist |
| Sonia Bass | VFX Artist |
| Vamsi Krishna Chilamkurthi | VFX Artist |
| Gary Christian | VFX Artist |
| Mauricio Cruz Alvarez | VFX Artist |
| Ruy Delgado | VFX Artist |
| Eduardo Dioses | VFX Artist |
| Komal Dogra | VFX Artist |
| Alana Douglas | VFX Artist |
| Phylicia Feldman | VFX Artist |
| Bruno Gagné | VFX Artist |
| Roberto Genito | VFX Artist |
| Lina Hum | VFX Artist |
| Rajnish Kumar | VFX Artist |
| Kosta Lagis | VFX Artist |
| Johnny Gidcomb | ADR Voice Casting |
| Emma Sands-Milsom | Casting Assistant |
| Jessica Cameron | Casting Associate |
| James Forsyth | Extras Casting |
| Ian Doig | Animal Coordinator |
| Jessica A. Gihon | Assistant Accountant |
| Veronika Skarlandtova | Assistant Accountant |
| Christopher J. Green | First Assistant Accountant |
| Greg Choi | Key Production Assistant |
| Corbin Heide | Key Production Assistant |
| Demi Karina Chew | Key Production Assistant |
| Murdoch MacNeil | Key Production Assistant |
| Trevor Zurkan | Key Production Assistant |
| Shannon Harron | Payroll Accountant |
| John Catron | Production Accountant |
| Tina Dawson | Production Accountant |
| Julie Sifuentes Etheridge | Production Coordinator |
| Bliss McDonald | Production Coordinator |
| Rachael Kent | Production Coordinator |
| Todd Rogers | Set Medic |
| Bárbara Morelos-Zaragoza | Translator |
| Rhett Reese | Writer |
| Paul Wernick | Writer |
| Vashi Nedomansky | Thanks |
| Jonathan Corn | Thanks |
| Gregor Robertson | Thanks |
| Jerry Dobrovolny | Thanks |
| Penny Ballem | Thanks |
| Sandi Swanigan | Thanks |
| Rob Liefeld | Thanks |
| Fabian Nicieza | Thanks |
| Patrick Doiron | Thanks |
| Rob Liefeld | Comic Book |
| Fabian Nicieza | Comic Book |
| Melissa R. Stubbs | Stunts |
| Rick Pearce | Stunts |
| Gui DaSilva-Greene | Stunts |
| Janene Carleton | Stunt Double |
| Owen Walstrom | Stunt Driver |
| Jodi Stecyk | Utility Stunts |
| Jason Bell | Stunts |
