 | Jack Johnson als Will Robinson |
 | Gary Oldman als Dr. Zachary Smith |
 | William Hurt als Prof. John Robinson |
 | Mimi Rogers als Dr. Maureen Robinson |
 | Lacey Chabert als Penny Robinson |
 | Matt LeBlanc als Maj. Don West |
 | Heather Graham als Dr. Judy Robinson |
 | Jared Harris als Older Will Robinson |
 | Mark Goddard als General |
 | Lennie James als Jeb Walker |
 | Marta Kristen als Reporter #1 |
 | June Lockhart als Principal Cartwright |
 | Adam Sims als Lab Technician |
 | Angela Cartwright als Reporter #2 |
 | John Sharian als Noah Freeman |
 | Abigail Canton als Annie Tech |
| Richard Saperstein als Global Sedition attack pilot |
| Dick Tufeld als Rambler-Crane series Robot (voice) |
 | Gary A. Hecker als Blarp (voice) |
 | Edward Fox als Businessman |
| Kamay Lau als Space Cadet Reporter |
| Mark W. Koch | Producer |
| Mike Fenton | Casting |
| Akiva Goldsman | Producer |
| Bruce Broughton | Original Music Composer |
| Stephen Hopkins | Producer |
| Peter Levy | Director of Photography |
| Akiva Goldsman | Screenplay |
| Allison Cowitt | Casting |
| Irwin Allen | Screenplay |
| Carla Fry | Producer |
| Stephen Hopkins | Director |
| Mary Selway | Casting |
| Steven Lawrence | Art Direction |
| Vin Burnham | Costume Design |
| Nick Palmer | Art Direction |
| Anna Pinnock | Set Decoration |
| David Lee | Art Direction |
| Ray Lovejoy | Editor |
| Alan Greenham | Standby Painter |
| Peter Bowen | Painter |
| Mike Roberts | Camera Operator |
| Pete Cavaciuti | Steadicam Operator |
| Sarah Robinson | Craft Service |
| Steve Shapland | Underwater Camera |
| Colin Manning | Key Grip |
| Brian Atkinson | Driver |
| Michael Schlingmann | Animation |
| Michael De Luca | Executive Producer |
| Kris Wiseman McIntyre | Co-Producer |
| Richard Saperstein | Executive Producer |
| Chris Carreras | Associate Producer |
| Michael Ilitch Jr. | Co-Executive Producer |
| Robert Rehme | Executive Producer |
| Tim Hampton | Co-Producer |
| Mace Neufeld | Executive Producer |
| Sharon Lark | Line Producer |
| Norman Garwood | Production Design |
| Jack English | Still Photographer |
| Steve Alder | Carpenter |
| Anne-Marie Challen | Stand In |
| Jerry Connelly | Electrician |
| Bruce Babcock | Orchestrator |
| Tim Caplan | I/O Supervisor |
| Kirstie Stephenson | Art Department Coordinator |
| Sue Hausner | Construction Coordinator |
| Billy Merrell | Best Boy Electric |
| Brent Brooks | Music Editor |
| Kim Amis | Sculptor |
| Yvonne Coppard | Makeup Artist |
| Keith Barton | Systems Administrators & Support |
| Lee Millham | Utility Stunts |
| Kevin Ahern | Visual Effects Editor |
| Tim Field | Production Manager |
| Clive Copland | Boom Operator |
| Ronald Eng | Sound Editor |
| Keith Pain | Supervising Art Director |
| Nigel Egerton | Assistant Costume Designer |
| Nikki Clapp | Script Supervisor |
| Simon Lucas | Rigging Gaffer |
| Iain Anderson | 3D Supervisor |
| Andy Fowler | Visual Effects Producer |
| Jane Body | Hairstylist |
| Bruce Everett | Post Production Supervisor |
| Julian Caldow | Production Illustrator |
| David White | Prosthetic Supervisor |
| Rodney Bowers | Post Production Assistant |
| Scott G.G. Haller | Sound Effects Editor |
| Ben Koeller | Video Assist Operator |
| David Combs | Studio Teachers |
| Elena Azuola | Production Controller |
| Dennis Davidson | Public Relations |
| Angus Bickerton | Visual Effects Supervisor |
| Graeme Crowther | Stunt Coordinator |
| Gina De Ferrer | Researcher |
| Robert Bell | Costume Design |
| Phil Attfield | Digital Effects Supervisor |
| Sarah Franzl | Stunts |
| Patric Scott | Unit Publicist |
| Nick Allder | Special Effects Supervisor |
| Carmila Gittens | Special Effects Coordinator |
| John Heath | Color Timer |
| Mike McGillivray | Gaffer |
| Martin Gabriel | Production Coordinator |
| Rosemary Burrows | Costume Supervisor |
| Eddy Joseph | Supervising Sound Editor |
| Uli Meyer | Animation Supervisor |
| Cheryl Bickerton | Visual Effects Coordinator |
| Paul Apted | First Assistant Sound Editor |
| Ron Bartlett | Sound Re-Recording Mixer |
| Colin Alway | Digital Compositors |
| Scott Sidey | Unit Manager |
| Thom 'Coach' Ehle | Dolby Consultant |
| Chris Carreras | First Assistant Director |
| Paul Grace | Technical Supervisor |
| Pauline Hume | Title Designer |
| Robert Grayson | Third Assistant Director |
| Renée Tondelli | Supervising ADR Editor |
| Julie Wright | Prosthetic Makeup Artist |
| Cliff Lanning | Second Assistant Director |
| Philip Alton | ADR Editor |
| Lee Clayton | Tailor |
| Louis Elman | ADR Voice Casting |
| Andrew Daffy | CG Animator |
| Tom Debenham | Visual Effects Designer |
| Peter Holt | Foley Editor |
| Gary Hutchings | Grip |
| Deanna Gould | Digital Effects Producer |
| Clare Macdonald | Assistant Production Coordinator |
| Steve Mair | Musician |
| Teri E. Dorman | Dialogue Editor |
| John Stephenson | Second Unit Director |
| David A. Arnold | Dialogue Editor |
| Pauline Griffiths | Foley Artist |
| Paula Boram | Foley Artist |
| David Balfour | Property Master |
| Ed Colyer | Foley Mixer |
| Suhail Kafity | Dialogue Editor |
| Patricia Carlin | Music Editor |
| Nik Korda | Unit Production Manager |
| Ed Hawkins | Compositing Supervisor |
| Graham Weames | Key Carpenter |
| Ian Green | Supervising Carpenter |
| Stephen Bettles | Special Effects Technician |
| Skip Margetts | Clapper Loader |
| Mike Sowa | Digital Color Timer |
| Marlon Cole | Dressing Prop |
| Nick Heather | Wardrobe Assistant |
| Melissa Byers | Camera Trainee |
| Simon Leech | Effects Supervisor |
| Simon Downes | Third Assistant Director |
| Stefan Adams | Property Buyer |
| Dean Forster | Stunt Double |
| Robb Bihun | Storyboard Artist |
| Brenda Coxon | Accountant |
| Micky Woolaard | Additional Gaffer |
| Derek Walker | Camera Loader |
| Steve Brooke Smith | Second Assistant Camera |
| Mark Goldberg | Rotoscoping Artist |
| Bob Bowen | Music Coordinator |
| Toby Earle | Floor Runner |
| Jane Royle | Assistant Makeup Artist |
| Gabriel Wells | Visual Effects Production Manager |
| Matthew Glen | Associate Editor |
| Brian Mcgivern | Generator Operator |
| Darren Howat | Graphic Designer |
| Alex Howe | Focus Puller |
| Bruce Broughton | Conductor |
| Richard Grills | Production Runner |
| Ted Swanscott | ADR Recordist |
| Julian Crowe | Digital Colorist |
| Ken Coles | Additional Director of Photography |
| William McPhail | Wardrobe Master |
| Tracey Gibbons | Post Production Coordinator |
| Chrissie Richardson | Assistant Accountant |
| Andrew Jack | Dialogue Coach |
| Michelle Corney | Production Assistant |
| Adrian Kays | Assistant Editor |
| Peter Talbot | Lighting Camera |
| Colin Clarke | Carpenter |
| Greg Powell | Stunt Coordinator |
| David Holmes | Stunts |
| Stefna Borges | First Assistant Editor |
