 | Natalie Portman als Lucy Cola |
 | Jon Hamm als Mark Goodwin |
 | Zazie Beetz als Erin Eccles |
 | Dan Stevens als Drew Cola |
 | Ellen Burstyn als Nana Holbrook |
 | Colman Domingo als Frank Paxton |
 | Nick Offerman als Will Plimpton |
 | Tig Notaro als Kate Mounier |
 | Pearl Amanda Dickson als Blue Iris |
 | Jeffrey Donovan als Jim Hunt |
 | Jeremiah Birkett als Hank Lynch |
 | Stella Edwards als Chelsea |
 | Arlo Mertz als Emily |
 | Tobias Schönleitner als Miles Henckle |
| Diana DeLaCruz als Dr. Addison |
| Cali DiCapo als Elementary School Girl |
 | Joe Williamson als Mayer Hines |
 | Arnell Powell als Earl Pearly |
| Rene H. Herrera als Nasa Safety Diver #1 |
 | Casey Adams als Nasa Safety Diver #2 |
| Rick Rottger als Nasa Safety Diver #3 |
| Sean Taylor als Nasa Safety Diver #4 |
 | Shay Ali als Test Engineer |
 | Zylan Brooks als Doctor |
 | Jake Dashnaw als San Diego Police #1 |
 | Chad Dashnaw als San Diego Police #2 |
 | Alyma Dorsey als San Diego Police #3 |
 | Ryan Ryusaki als San Diego Police #4 |
 | Mic Rodgers als San Diego Police #5 |
 | Jay Hieron als San Diego Police #6 |
| Brittany Berryman als Gas Station Mom |
| Aiden Berryman als Gas Station Boy #1 |
 | Jonny Berryman als Gas Station Boy #2 |
 | Nicole Dele als Store Clerk |
 | Rasha Goel als News Anchor |
| Brian C. Brown | Writer |
| Elliott DiGuiseppi | Writer |
| Reese Witherspoon | Producer |
| Bruna Papandrea | Producer |
| Noah Hawley | Director |
| Noah Hawley | Producer |
| John Cameron | Producer |
| Molly Allen | Executive Producer |
| Brian C. Brown | Executive Producer |
| Elliott DiGuiseppi | Executive Producer |
| Jeff Russo | Original Music Composer |
| Polly Morgan | Director of Photography |
| Regis Kimble | Editor |
| Ronna Kress | Casting Director |
| Stefania Cella | Production Design |
| Samantha Avila | Art Direction |
| Jon J. Bush | Set Decoration |
| Louise Frogley | Costume Design |
| D'Shanna Moses | Art Department Coordinator |
| Brian C. Brown | Story |
| Elliott DiGuiseppi | Story |
| Noah Hawley | Writer |
| Amy Schmiederer | Key Makeup Artist |
| Cindy J. Williams | Makeup Department Head |
| Veda Semarne | Script Supervisor |
| Terry Woodcock | Driver |
| Steve Villasenor | Driver |
| Terri Greening | Accountant |
| Jascha Dlugatch | Set Medic |
| James Crowley | Location Scout |
| Mandi Dillin | Location Scout |
| Jennifer Dunne | Location Manager |
| Paul Knaus | Location Scout |
| Deb Downing | Costumer |
| Nicole Leitner | Costumer |
| Bob Moore Jr. | Set Costumer |
| Lily Scott | Set Costumer |
| Emma Sands-Milsom | Casting Associate |
| Lauren Richer | Casting Coordinator |
| Laura Drake Mancini | Extras Casting Coordinator |
| Hilary Bronwyn Gayle | Still Photographer |
| Dixie Webster | Extras Casting |
| Leigh Kittay | Executive Producer |
| Ronna Kress | Casting |
| Maggie Phillips | Music Supervisor |
| John Cameron | Unit Production Manager |
| Donald Murphy | First Assistant Director |
| Peter Dress | Second Assistant Director |
| Casey Adams | Stunts |
| Oliver Keller | Stunts |
| Chad Dashnaw | Stunts |
| Natalie Padilla | Stunt Double |
| Jake Dashnaw | Stunts |
| Sherry Rene | Stunt Double |
| J.J. Dashnaw | Stunts |
| Jeffrey J. Dashnaw | Stunt Coordinator |
| Wesley Scott | Stunts |
| Nikki Stanley | Stunts |
| Jeremy Fitzgerald | Stunts |
| Peggy Robinson | Production Supervisor |
| Aja Kai Rowley | Assistant Art Director |
| Michael Timman | Leadman |
| David Agajanian | Set Dresser |
| R. Henry Evans | Set Dresser |
| Chris Larsen | Set Dresser |
| Sarai Sosa | Set Dresser |
| John Warner | Set Dresser |
| Daniela Medeiros | Set Designer |
| Shamim Seifzadeh | Set Designer |
| Elizabeth Maines | Art Department Assistant |
| Megan Soderberg | Set Decoration |
| Ellen Dorros | Set Decoration Buyer |
| Jane Madden | Set Decoration Buyer |
| Denise Anderson Poore | Second Second Assistant Director |
| Mitch Dubin | Camera Operator |
| Sarah Levy | Camera Operator |
| Peter Rosenfeld | Steadicam Operator |
| Dean Morin | First Assistant Camera |
| Cheli Clayton | First Assistant Camera |
| Kevin Miles | Second Assistant Camera |
| Veronica Bouza | Second Assistant Camera |
| Chris Cavanaugh | Digital Imaging Technician |
| George Ballenger | Camera Loader |
| Ed Novick | Production Sound Mixer |
| Michael Piotrowski | Boom Operator |
| Kelly Lewis | Utility Sound |
| Joan Kelley Bierman | Post Production Supervisor |
| Robin August | First Assistant Editor |
| Misha Syeed | Assistant Editor |
| Kurt Leitner | Post Production Coordinator |
| Ai-Ling Lee | Sound Re-Recording Mixer |
| Ai-Ling Lee | Sound Designer |
| Ai-Ling Lee | Supervising Sound Editor |
| Tobias Poppe | Sound Designer |
| Tobias Poppe | Supervising Sound Editor |
| Andy Nelson | Sound Re-Recording Mixer |
| Michael Ambrose | Gaffer |
| Morten Petersen | Best Boy Electric |
| Ffilip Bolton | Electrician |
| Darryl Cowherd | Electrician |
| Christopher Pritzlaff | Electrician |
| Roberto Schein | Electrician |
| Dana Arnold | Rigging Gaffer |
| Rick Senteno | Best Boy Electric |
| Manny Duran | Key Grip |
| Raul Vasquez | Best Boy Grip |
| Brad Rea | Dolly Grip |
| Michael Wahl | Dolly Grip |
| Randy Garcia | Grip |
| Danny Sosa | Grip |
| Eddie G. Gutierrez | Key Rigging Grip |
| Camille Argus | Costume Supervisor |
| Garet Reilly | Key Costumer |
| Parrish Kennington | Set Costumer |
| Ariel Thomas | Costume Assistant |
| Jacklin Masteran | Key Hair Stylist |
| Huyen Tran | Hairstylist |
| Ian Rutherford | Assistant Location Manager |
| Nathan Stein | Assistant Location Manager |
| Ben Thomas Holley | Assistant Location Manager |
| Christina Conway | Assistant Location Manager |
| Trish Gallaher Glenn | Property Master |
| Monica Castro | Assistant Property Master |
| Azra Bano Ali | Assistant Property Master |
| Jacquelyn Gutierrez | Props |
| Mark R. Byers | Special Effects Coordinator |
| Jonas Kirk | Construction Coordinator |
| Carrie Roslan | Construction Buyer |
| Shari LaFranchi Blakney | Production Coordinator |
| Lee Perez-Gonzalez | Assistant Production Coordinator |
| Kris Chaney | Production Secretary |
| Terri Greening | Production Accountant |
| Meara McDonald | First Assistant Accountant |
| Christopher Ciketic | Assistant Accountant |
| Emily Thorne | Assistant Accountant |
| Irina Naydichev | Payroll Accountant |
| Kimberly Latina | Transportation Coordinator |
| Bryan Northup | Transportation Captain |
| Vincent Lira | Transportation Co-Captain |
| Brooke Ensign | Unit Publicist |
| Monika Manson | Set Medic |
| Lou Pecora | Visual Effects Supervisor |
| Susan Dawes | Supervising ADR Editor |
| Susan Dawes | Dialogue Editor |
| Galen Goodpaster | Supervising ADR Editor |
| Helen Luttrell | Dialogue Editor |
| David V. Butler | ADR Editor |
| Jon Title | Sound Effects Editor |
| Dan Kenyon | Sound Effects Editor |
| Lee Gilmore | Sound Effects Editor |
| Justin M. Davey | Foley Editor |
| Melissa Lytle | Assistant Sound Editor |
| Steve Baine | Foley Artist |
| Peter Persaud | Foley Mixer |
| Samuel R. Green | Sound Engineer |
| Geoff Ethridge | Sound Engineer |
| David Betancourt | ADR Mixer |
| Charleen Richards-Steeves | ADR Mixer |
| Christine Sirois | ADR Recordist |
| David Lucarelli | ADR Recordist |
| Evan Rautiainen | ADR Engineer |
| Jeff Russo | Conductor |
| Amie Doherty | Orchestrator |
| Matt Decker | Music Editor |
| Christine Greene Roe | Music Coordinator |
| Allan Padelford | Stunt Driver |
