 | Shah Rukh Khan als Shekhar Subramaniam / G.One |
 | Arjun Rampal als Ra.One |
 | Kareena Kapoor Khan als Sonia S. Subramanium |
 | Armaan Verma als Prateek |
 | Tom Wu als Akaashi |
 | Shahana Goswami als Jenny Nayar |
 | Dalip Tahil als Barron |
 | Satish Shah als Iyer |
 | Suresh Menon als Taxi Driver |
 | Atul Sharma als Airport security guard |
 | Ben Hawkey als Billy |
 | Delnaaz Irani als School teacher |
| Charanpreet Singh als Airport goon |
 | Priyanka Chopra Jonas als Desi Girl |
 | Sanjay Dutt als Khalnayak |
 | Shola Adewusi als Airport Cop |
 | Paul Lowe als Mugger |
 | Georgia Curtis als Backing Dancer |
 | Rajinikanth als Chitti / Himself |
 | Amitabh Bachchan als Self - Narrator (voice) |
| Mustaq Sheikh | Screenplay |
| Kanika Dhillon | Screenplay |
| Anubhav Sinha | Director |
| Gauri Khan | Producer |
| Anubhav Sinha | Screenplay |
| Bobby Chawla | Producer |
| Anubhav Sinha | Story |
| David Benullo | Screenplay |
| Resul Pookutty | Sound Designer |
| Denney Pierce | Stunts |
| Kim Do Nguyen | Stunt Double |
| Kanal Kannan | Thanks |
| Haresh Hingorani | Visual Effects Supervisor |
| Nicola Pecorini | Director of Photography |
| V. Manikandan | Director of Photography |
| Pompy Hans | Makeup Artist |
| Ritesh Naik | Makeup Artist |
| Paul Lowe | Stunt Double |
| Susheel Peris | Visual Effects Supervisor |
| Praveen Bareria | Visual Effects |
| Snehil Pandey | Visual Effects |
| Vishal Dadlani | Original Music Composer |
| Yang Liang | Stunt Double |
| Keith Devlin | Visual Effects Supervisor |
| Sanjiv Chawla | Executive Producer |
| Niranjan Iyengar | Dialogue |
| Arjun Mitra | Visual Effects |
| Sanjay Sharma | Editor |
| Spiro Razatos | Stunts |
| Garman Herigstad | Visual Effects |
| Gabriel Nunez | Stunt Double |
| Chianjeevi Yerra | Visual Effects |
| Sabu Cyril | Art Direction |
| Shah Rukh Khan | Producer |
| Parvez Khan | Stunts |
| Supriya Avate | Visual Effects Supervisor |
| Martin Walsh | Editor |
| Paul Gorrie | Special Effects Coordinator |
| Firaz Boss | Stunt Coordinator |
| Sid Jayakar | Visual Effects Supervisor |
| Shekhar Ravjiani | Original Music Composer |
| Doug Coleman | Stunts |
| Jason Hunjan | Stunts |
| V. Srinivas Mohan | Visual Effects Supervisor |
| Nick Dent | Art Direction |
| Karan Johar | Thanks |
| Kanika Dhillon | Dialogue |
| Manish Malhotra | Costume Design |
| Tarun Mansukhani | Thanks |
| Sunil Lulla | Co-Producer |
| Amrit Pritam Dutta | Sound Designer |
| Sal Ammytrauern | Animation |
| Santosh Kotkar | Art Direction |
| Prasun Mukherjee | Casting Director |
| Marcus Shakesheff | Stunts |
| Shafqat Amanat Ali | Playback Singer |
| Akon | Playback Singer |
| Vivek Soni | Visual Effects Coordinator |
| Anvita Dutt | Lyricist |
| Debbie Evans | Stunt Driver |
| Andy Gill | Stunt Coordinator |
| Andy Gill | Second Unit Director |
